Research articles
ScienceAsia (): 141-144 |doi:
10.2306/scienceasia1513-1874...141
Detection and confirmation of hispolon in the mushroom Phellinusÿlinteus
PadungratÿToopmuanga, ChutaratÿKhamchuma,b, VittayaÿPunsuvona,b,c,*
ABSTRACT: Phellinus linteus (PL), a mushroom known as krathin phiman in Thai, has been used as a traditional medicine in the treatment of various cancers. Hispolon obtained from PL ethanol extracts is a promising anti-cancer compound. In this study, ethanol concentration and extraction time were varied for a soxhlet extraction. The content of hispolon in a crude extract was determined by high performance liquid chromatography with a UV detector. The presence of hispolon in the crude extract was demonstrated by liquid chromatography-tandem mass spectrometry (LC-MS/MS) with daughter ion scanned mode. The results showed that both hispolon and Thai PL have a similar parent ion at m/z 218.91 and daughter ions at m/z 176, 160, 135.
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| a |
DepartmentÿofÿChemistry, FacultyÿofÿScience, KasetsartÿUniversity, Bangkokÿ10900ÿThailand |
| b |
CentreÿofÿExcellent-OilÿPalm, KasetsartÿUniversity, Bangkokÿ10900ÿThailand |
| c |
CentreÿofÿAdvancedÿStudiedÿinÿTropicalÿNaturalÿResource, NRU-KU, KasetsartÿUniversity, Bangkokÿ10900ÿThailand |
* Corresponding author, E-mail: fscivit@ku.ac.th
Received 6 Aug 2013, Accepted 7 Jan 2014
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