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Research articles

ScienceAsia 43(2017): 281-288 |doi: 10.2306/scienceasia1513-1874.2017.43.281


Anti-hyperglycaemic and anti-hyperlipidaemic effects of black and red rice in streptozotocin-induced diabetic rats


Payungsak Tantipaiboonwonga,*, Komsak Pinthaa, Wittaya Chaiwangyena, Teera Chewonarinb, Kanjana Pangjitc, Orada Chumphukama, Napapan Kangwand, Maitree Suttajita

 
ABSTRACT:     Increasing numbers of diabetic patients, especially those with type II, can link their condition to changes in eating habits. Black rice and red rice are not only a source of carbohydrate but also rich sources of antioxidants, especially proanthocyanidins and anthocyanins. This study determines the effect consuming a black rice extract (BRE) or a red rice extract (RRE) on streptozotocin-induced diabetic rats. Blood levels of glucose, triglycerides, and cholesterol in the diabetic group were determined and compared to that of the control group. The results demonstrate that consumption of BRE, 50 mg/kg body weight (BW), or RRE, 100 mg/kg BW, could significantly reduce the blood glucose level of the diabetic rats after eight weeks. Consumption of BRE, 100 mg/kg BW or RRE, 50 mg/kg BW, also clearly decreased the triglyceride level. The cholesterol level in the diabetic group fed with BRE or RRE decreased as well. Thus daily consumption of black rice, red rice, or having their extracts in food supplements may prevent the onset of diabetes.

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a Division of Biochemistry and Nutrition, School of Medical Sciences, University of Phayao, Phayao, Thailand 56000
b Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand 52000
c College of Medicine and Public Health, Ubon Ratchathani University, Ubon Ratchathani, Thailand 34190
d Division of Physiology, School of Medical Sciences, University of Phayao, Phayao, Thailand 56000

* Corresponding author, E-mail: payungsak.t@gmail.com

Received 8 May 2017, Accepted 9 Nov 2017