| Home  | About ScienceAsia  | Publication charge  | Advertise with us  | Subscription for printed version  | Contact us  
Editorial Board
Journal Policy
Instructions for Authors
Online submission
Author Login
Reviewer Login
Volume 43 Number 3
Volume 43 Number 2
Volume 43 Number 1
Volume 43S Number 1
Volume 42 Number 6
Volume 42S Number 1
Earlier issues
Volume 41 Number 1 Volume 41 Number 2 Volume 41 Number 3

previous article next article 1

Research articles

ScienceAsia 41(2015): 108-113 |doi: 10.2306/scienceasia1513-1874.2015.41.108


Increasing the discrimination power of a mitochondrial DNA control region by using hypervariable region˙2 polymorphisms, as illustrated in Tai populations of Northern Thailand


Chaiwat˙Kriengchutimaa, Nadchanok˙Rodrussameea, Wibhu˙Kutananb, Jatupol˙Kampuansaia,*

 
ABSTRACT:     Nucleotide sequences of the mitochondrial DNA hypervariable region˙2 (HVR2) of five Tai speaking populations, Khuen, Lue, Tai Yai, Yong, and Yuan, living in the upper northern part of Thailand were analysed. Based on a comparison of 268-bp sequences in 124 people, 32 polymorphic sites, and 52 different sequence types were observed. The HVR2 possessed lower polymorphism than HVR1 of the same populations. However, when the two regions were combined, the discrimination power increased and could distinguish most of the Tai populations as well as separate the Tai from the neighbouring Mon-Khmer speaking populations. The Tai showed fewer genetic differences than those of the Mon-Khmer. This might have been a result of the admixture process across the Tai ethnic groups. The increasing of genetic polymorphism and discrimination power of the combined HVR1 and 2 data would enhance the accuracy and efficiency of personal and ethnicity identifications.

Download PDF

0 Download 45 View


a Department˙of˙Biology, Faculty˙of˙Science, Chiang˙Mai˙University˙50200˙Thailand
b Department˙of˙Biology, Faculty˙of˙Science, Khon˙Kaen˙University˙40002˙Thailand

* Corresponding author, E-mail: Jatupol.k@cmu.ac.th

Received 15 Nov 2014, Accepted 13 Feb 2015