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Volume 39 Number 3 Volume 39 Number 4 Volume 39 Number 5

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Research articles

ScienceAsia 39(2013): 340-345 |doi: 10.2306/scienceasia1513-1874.2013.39.340

Phenolic acid content, antioxidant properties, and antibacterial potential of flowers and fruits from selected Pakistani indigenous medicinal plants

Syed Ali Raza Naqvia,*, Rifaqat Waseema, Nasir Mahmoodb, Zaib Hussainc, Zulfiqar Ali Khana, Sohail Anjum Shahzadd, Muhammad Yare, Rashid Amine, Shazia Anwer Bukharia, Ameer Fawad Zahoora, Sadia Javeda, Abdullah Ijaz Hussainf

ABSTRACT:     Biological evaluation of Lantana camara and Justicia adhatoda, belonging to the medicinal plant families Verbenaceae and Acanthaceae, respectively, was performed. Both plants contain a very good range of phenolic compounds (20.5±1.9–80.9±4.1 mg GAE/g of dry extract). HPLC analysis of Justicia adhatoda flower and fruit extract showed a broad profile of phenolic acids such as p-hydroxy benzoic acid, syringic acid, gallic acid, and quercetin in substantial amounts. The antioxidant study showed moderate to good ability to inhibit linoleic acid peroxidation and to scavenge DPPH free radicals (67.5±4.7 to 80.4±3.0% and 71.3±3.8 to 85.9±2.0%, respectively). The antibacterial study reflected good antibacterial potential. This study showed that extracts of flowers and fruits of both plants grown in Soon Skaser Valley, Pakistan have a strong potential to scavenge free radicals and may be used to develop functional food and herbal medicines to treat oxidative stress diseases and bacterial infections.

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a Department of Chemistry, Government College University, Faisalabad-38000, Pakistan
b Department of Allied Health Sciences and Chemical Pathology, University of Health Sciences, Lahore-54000, Pakistan
c Institute of Chemistry, University of the Punjab, Lahore-5400, Pakistan
d Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad-22060, Pakistan
e Interdisciplinary Research Centre in Biomedical Materials, COMSATS Institute of Information Technology, Lahore-54000, Pakistan
f Department of Applied Chemistry, Government College University, Faisalabad-38000, Pakistan

* Corresponding author, E-mail: a_naqvi313@yahoo.com

Received 15 Nov 2012, Accepted 27 Feb 2013