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Short Report

ScienceAsia 17 (1991): 141-149 |doi: 10.2306/scienceasia1513-1874.1991.17.141

 

DETERMINATION OF ACIDITY AND BASICITY CONSTANTS OF N-ACETYL-PEPTIDE COMPOUNDS

 

VITHAYA RUANGPORNVISUTI

ABSTRACT: Acidity and basidty constants of N-acetyI-lalanine, N-acetyI-l-histidine, N-acetyl-l-lysine, and N-acetyl-I-valine have been determined by means of potentiometric titration. The titrations have been observed at 25 oC and ionic strength of 0.5 M potassium nitrate. The equilibrium constant of these N-acetyl-pepetide compounds were obtained by computer refinements.

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Department of Chemistry, Faculty of Science, ChulaIongkom University, Bangkok, Thailand 10330

Received 15 August 1991