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Research articles

ScienceAsia 44 (2018): 11-17 |doi: 10.2306/scienceasia1513-1874.2018.44.011


Interfacial tension of turmeric nanoparticles


Sakchai�Auychaipornlerta, Pojawon�Prayurnprohm�Lawanpraserta,*, Suchada�Piriyaprasarthb, Pongtip�Sithisarnc

 
ABSTRACT:     The dried rhizome of turmeric (Curcuma longa) is a source of volatile oil and curcuminoids. Curcumin, the major component, has a wide spectrum of pharmacological activities. Various advanced techniques have been proposed to improve the efficacy of curcumin, especially nanoparticles formation techniques. In this study, we prepared turmeric spherical particles in an alcoholic water system to investigate their physicochemical properties. Turmeric spherical particles were in a nanometre size range with a narrow size distribution and negative surface charge. Additionally, we proposed an equation derived from the Young-Laplace equation which appears to be applicable to estimate an interfacial tension value of turmeric nanoparticles and other microemulsion systems.

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a Department�of�Manufacturing�Pharmacy, Faculty�of�Pharmacy, Mahidol�University, Bangkok�10400�Thailand
b Department�of�Pharmaceutical�Technology, Faculty�of�Pharmacy, Silpakorn�University, Nakhon�Pathom�7300, Thailand
c Department�of�Pharmacognosy, Faculty�of�Pharmacy, Mahidol�University, Bangkok�10400�Thailand

* Corresponding author, E-mail: pojawon.pra@mahidol.ac.th

Received 12 Jun 2017, Accepted 23 Nov 2017