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Volume 36 Number 4 Volume 37 Number 1 Volume 37 Number 2

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ScienceAsia 37 (2011): 72-74 |doi: 10.2306/scienceasia1513-1874.2011.37.072

Preliminary investigation of the angiogenic potential of Ziziphus oenoplia root ethanolic extract using the chorioallantoic membrane model

Susovan Sinha Mahapatra, Satyaranjan Mohanta, Amit Kumar Nayak*

ABSTRACT:     The angiogenic potential of an ethanolic extract of Ziziphus oenoplia root was evaluated by the chick chorioallantoic membrane (CAM) model (in vitro) in 9 days old fertilized chick eggs. The tested extract was found to increase the number of capillaries on the treated CAM surfaces from three 9 days old fertilized chick eggs. These findings suggested that the ethanolic extract of Z. oenoplia root possesses significant angiogenic potential, which may be beneficial in the treatment of wound healing.

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P.G. Department of Pharmacy, Seemanta Institute of Pharmaceutical Sciences, Jharpokharia, Mayurbhanj-757086, Orissa, India

* Corresponding author, E-mail: amitkrnayak@yahoo.co.in

Received 18 Aug 2010, Accepted 10 Feb 2011